A 1998 meta-analysis study from Nutrition and Cancer

Whole Grain

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Summer 2008 Black pepper inhibits colon cancer cell proliferation

A study at St. Louis University in Missouri was designed to determine if black pepper, resveratrol from grapes, and cinnamaldehyde from cinnamon have anti-prolific effects on colon cancer. Quantitative effects of each substance on concentration responses and time courses of proliferation of cultured human colon cancer cells were assessed.

Black pepper showed significant anti-proliferative activity at 24, 48 and 72 hours following administration.

(Clinical Laboratory Science, Summer, 2008)

9/04 Researchers now believe too many colonoscopies are done too soon after polyps are removed. "New research suggests that many gastroenterologists and surgeons are performing surveillance colonoscopy after polypectomy in excess of guidelines, especially for low-risk lesions and hyperplastic polyps." (MEDSCAPE, 9/04)

"Whole-Grain Intake and Cancer: An Expanded Review and Meta-Analysis" David R. Jacobs, Jr, Leonard Marquart, Joanne Slavin, Lawrence K. Kushi

Consumption of phytochemical-rich plant foods, including whole grains, fruits, and vegetables, has been observed to be associated with reduced risk for certain cancers. Whole grains, which contain micronutrients and nonnutrients lost in the refining process, may have health associations different from refined grains. We previously reviewed 14 case-control studies of colorectal, gastric, and endometrial cancers and found reduced risk in high compared to low whole-grain intake in 18 of 21 mentions.

Unknown constituents of whole grain may be protective, or constituents may act synergistically. In any case, whole foods such as whole grains deliver packages of nutrients and nonnutrients that may work together to protect human health, and factors in addition to dietary fiber appear to elicit the health benefits of whole grains.

Although it would be scientifically desirable to conduct clinical trials of whole-grain intake and cancer prevention to fully assess confounding as an explanation of these findings, such trials may not be feasible because of their required size, cost, and duration. Study of the biologic effects of whole grain and its constituents is more feasible and should be pursued vigorously. Nevertheless, the findings of the present review, taken together with known beneficial action of many nutrients contained in whole grains and the possibility of synergistic action of nutrients packaged in their natural form, suggest that it would be prudent for the public to eat more whole-grain foods. Nutrition and Cancer vol 30(2):85-96 1998


Colorectal Cancer Groups

Chewing Gum Relieves Ileus After Colorectal Surgery

Diet Appears to Influence Colon Cancer OUTCOMES

Stage III Colon Cancer Pts Western vs Prudent Diet
Olive Oil & Colon Cancer

Olive Oil, Intestinal Cancer
DHA Suppresses Colon Tumors
Sentinel Node for Colon Cancer

Digital Rectal Exam:Colorectal Alert test
Left Colon Tumors Differ Genetically from Right
Lymphatic Mapping: Colon
Dietary Factors in Human Colorectal Cancer

Euro Prospective Study: Meat, Fish, Colorectal Ca Risk
Eat Less & Eat Healthier (+ Exercise)
Fruit/Veg & Risk of Colorectal Ca (in BCA Cohort)
Vegs, Tea, Soy on N-Nitrosation
Dietary Patterns & Risk of Colon Ca
Refined Cereal/High-Fat Animal Products RISK
Food as Risk Factors Colon Adenomas (France)
Egg Consumption & Mortality:Colon/Rectal Ca
Vegetarians and Colorectal Cancer Incidence
Omega3 Polysaturated Oil & Colon Ca
Antitumor Effects: Combo Tea
Nutritional Habits from Ulcerative Colitis - CA Development
Functional food ingredients against colorectal cancer - 'Omics'
Implementation of a Healthy Diet (over 4 Years)

Physical Exercise/Plantago ovata/Aspirin:ColonCa Risk
Dietary Indoles/Isothiocyanates Useful for Colon Ca

Anthocyanin-rich Extracts:Aronia meloncarpa E. Colon
Grape Seed Extract Inhibits Colon Ca Cells
Green Tea, Phytic Acid, & Inositol (in rats): colon tumors
Milk Intake, Insulin-like growth Factor and Risk of Colon Ca/Men

Insulin, Insulin-Like Growth Factor & Colon Ca:review of evidence
Carageenan and Colon Cancer

Trans-Fatty Acids & Colon Ca

Dietary Fiber & Carcinogenesis

Soluble & Insoluble Fiber Roles
Fruits/vegetables NOT Fiber Supplements
Dietary Fiber LOWERS Colon Cancer Risk
Grape Seed Proanthocyanidins & Colon

Dietary CLA & Apoptosis (Rats)

Dietary CLA Inhibits Colon Crypt Foci
HRT & Colorectal Adenoma Recurrence in Women

Women with Colorectal and Endometrial Cancer
New Guidelines: Testing Hereditary Colorecal Ca/Other Ca Risks
Mechanisms/Anticarcinogenic Effects of Diet-Related Cell Death

Daily Multivitamin With FOLATE

Folinic Acid Part of Colorectal Therapy
Colorectal Protocol
Vitamin D Fights Colon Cancer

Vitamin D-rich Diet Protects From Colon Ca
Vitamin D Helps Colorectal Cancer Patients: Study
Vitamin E succinate-colon ca cells

Flavinoids & Colon CA Cells

Citrus Liminoids In Colon Ca Prevention
resveratrol & quercetin protect cells from exogenous pro-oxidative damage
Tongue Diagnosis for Colon Cancer?

Tumor Specifics Found in Stool: Test for Colon Ca

Deguelin Inhibits Growth of Cells

Preventive Effect of Fermented Brown Rice/Rice Bran

Rice Germ Prevents Colon Carcinogenesis
Wheat Germ Extract Inhibits Colon Carcinogenesis
Dietary Capsaicin & Rotenone for Chemoprevention

Diarrhea & Colon Cancer

Bowel Movement Frequency & Colorectal Ca
Nuts, Corn, & Popcorn & Incidence of Diverticular Disease
Green/White Tea = NSAIDS & Colon Tumors

Effects of Natural Chemoprevention in Human Colon Ca Cells

Fish & Mltivits & Reduced Colo Ca Risk
Chemopreventive Agents of Plant Origin:Colon Ca
Colon Ca Cell Growth Inhibited by Various Berries
Magnesium Intake: Colorectal Risk in Women
Pharmacodynamic Action & Colonic Levels Curcumin

Chemosensitization of Paclitaxel by Ginseng (Element)
Curcumin & Irreversible Growth Inhibition/Apoptosis:Melanoma
Social Networks & Long-term Colorectal Survivors (Women)

Colon Cancer Abstracts

Gamma-Tocopherol Better alpha-Toco for Human Colon Ca Cells
Urban-Rural Diff in Colon Ca Risk: Bk/Wh
White Tea/Sulindac Chemopreventive Mouse Colon Ca
Antocyanin Extracts:Human Colon Ca Cells & Rat Ca
Prebiotic Treatment & Colon Ca (Rats)
High Energy LET Radiation & Colon Carcinogenesis
Pharmacology of Curcumin
Assoc of Ampullary & Colorectal Malignancies

RTx-Induced Apoptosis & Rectal Ca

Night-Shift=Melatonin Deficiency=Colorectal Ca Risks

Genetic Signature May Predict Recurrence: Colon Ca

Sentinel Node Mapping: Colorectal Cancer
Gene Analysis for Chemotherapy Benefits: Colon Cancer
African-Americans More Likely to Die of Colon Ca

Racial Diff in Survival: Tumor Diff/Stage Colon Ca
Nutritional Intervention RTx & Pelvic Malignancy-NEEDS STUDY

Siblings Needed For Colon Cancer Study

RCT Adjvt TX Colon Ca: 10 Yr Results Surg=Chemo=Immuno

Treating EGFR Rash BEFORE It Appears:Clinical Trial
Terminalia catappa (Herb) is Chemopreventive (Rats) Colon

Morning Colonoscopies BETTER

Virtual Colonoscopies
FDA MedWatch: DO NOT USE these OTCs BEFORE Colonoscopy
Sexual Dysfunction AFTER Rectal Ca Surgery

Effects of Ascorbic Acid on Rectal Polyps:Familial Polyposis

References for Ascorbic Acid and Familial Polyposis
Chinese Medical Herbs for Chemo 'Side' Effects:Colorectal

Protocol: Talk to Your Doctor: Colon Cancer

Immune Supression & Colorectal Cancer

Natural Killer Cells Made, NOT Born
Nontoxic Immune Enhancers

Calcium & Vit D May Reduce Risk of Adenoma Recurrence
Chemoprevent Colon Ca:Calcium, Vit D & Folate
Adding IV Calcium & Magnesium to therapy with Oxaliplatin
Oral Glutamine Effective Prevents Oxaliplatin-Induced Neuropathy Colorectal Ca Pts

Patient perspective on Ileostomy

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