April 2011 Press Release from Intermountain Medical Center Heart Institute, Murray, Utah
Fasting "not only lowers one’s risk of coronary artery disease and diabetes, but also causes significant changes in a person’s blood cholesterol levels. Both diabetes and elevated cholesterol are known risk factors for coronary heart disease.
The discovery expands upon a 2007 Intermountain Healthcare study that revealed an association between fasting and reduced risk of coronary heart disease, the leading cause of death among men and women in America. In the new research, fasting was also found to reduce other cardiac risk factors, such as triglycerides, weight, and blood sugar levels.
The findings were presented Sunday, April 3, at the annual scientific sessions of the American College of Cardiology in New Orleans. Dr. Benjamin D. Horne, PhD, MPH, director of cardiovascular and genetic epidemiology led the study.
Unlike the earlier research by the team, this new research recorded reactions in the body’s biological mechanisms during the fasting period. The participants’ low-density lipoprotein cholesterol (LDL-C, the “bad” cholesterol) and high-density lipoprotein cholesterol (HDL-C, the “good” cholesterol) both increased (by 14 percent and 6 percent, respectively) raising their total cholesterol – and catching the researchers by surprise.
Acute Fast Does Not Induce Compensatory Energy and Nutrient Intake
A DGReview of :"Effect of an acute fast on energy compensation and feeding behaviour in lean men and women."
By James Adams
A 36-hour fast does not induce a significant compensatory response in energy and nutrient intake on the subsequent day.
Previous studies have shown that severe restriction of dietary energy consumption resulting in 5 to 30 percent weight loss often leads to hyperphagia and weight regain in lean subjects, according to investigators, from the Rowett Research Institute in Aberdeen, United Kingdom.
To determine the effect of 26 hours of fasting on compensatory behaviour, they studied 24 healthy, lean men and women, who underwent a 36-hour fasting period and a 36-hour maintenance period.
On the day before the fast subjects consumed a diet designed to avoid overeating, then for 36 hours they consumed only non-energy drinks. Following the fast, subjects were allowed to eat what they wanted from a variety of familiar foods.
The maintenance treatment was identical to the fasting protocol, except that subjects received a defined maintenance diet during the 36-hour period.
Results showed that average energy intake was 12.2 MJ/day on the day following the 36-hour fast (p=0.049). Average energy intake was 10.2 MJ/day on the day following the maintenance protocol.
Feeding behaviour was altered only at breakfast following the fast, when subjects selected a higher-fat meal compared with their breakfast selection after the maintenance protocol (p<0.005). Motivation to eat was higher during the fast, but returned to baseline levels following the post-fast breakfast (p<0.05).
The investigators conclude that a 36-hour fast does not induce a powerful, unconditional stimulus to compensate on the subsequent day.
Int J Obes Relat Metab Disord 2002; 26(12): 1623-1628.
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Nutrition Journal 2010, 9:57doi:10.1186/1475-2891-9-57
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