Low-Dose Photodynamic Therapy Treats 

Cancer Cells Deep in Chest Walls

Photodynamic therapy (PDT), one of the most promising new cancer treatments, may have much wider application than previously thought, new research by University at Buffalo researchers has shown.

Thomas S. Mang, Ph.D., UB clinical associate professor of oral and maxillofacial surgery, has found that by manipulating the amount of a light-sensitive drug and the intensity of the laser beam that activates it, he can successfully treat cancer cells deeply embedded in the chest wall without damaging surrounding normal tissue.

This low-dose PDT approach has resulted in complete healing in nearly 90 percent of 102 recurrent breast-cancer lesions.

Dr. Mang presented his findings on April 8, 2000 at the annual meeting of the American Society for Laser Medicine and Surgery.

Ann's NOTE: In 1998 met with a doctor at Brigham & Women's Hospital in Boston to discuss photodynamic therapy (PDT). At that time I was told that the technique could only be used in larger tumors on the skin surface. However he felt that the future was in working with brain and other organs. Tumors that could not easily be reached without extensive surgery were the target.

This is also being looked at in Chicago and San Francisco. Check out the NCI website for clinical trials for more information. http://cancertrials.nci.nih.gov/

This is local control only and would need to be combined with a dietary and nutritional program for best impact.

Thanks to the Doctor's Guide for this information


PDT for Chest Wall Tumors

Intl J Rad Onc, Bio, Phy, 11/02


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