"Supplementation with oral probiotic bacteria protects human cutaneous immune homeostasis after UV exposure-double blind, randomized, placebo controlled clinical trial"
Peguet-Navarro J, Dezutter-Dambuyant C, et al,
(Address: Université de Lyon, EA 41-69, Hôpital Edouard Herriot, Pavillon R, Département Dermatologie, Lyon, France. E-mail: email@example.com ).
Summary: In a randomized, double-blind, placebo-controlled clinical trial involving 54 healthy adults, supplementation with the probiotic, Lactobacillus johnsonii (La1), for 6 weeks prior to solar-simulated UV irradiation was found to "accelerate the recovery of skin immune homeostasis."
While UV-induced phenotypic maturation of Langerhans cells was not prevented among subjects who consumed the probiotic supplement, by day 4 post-exposure, the allostimulatory capacity of epidermal cells was completely recovered among subjects who consumed the probiotic supplement, "correlating with the normalization of CD1a expression within the epidermis."
These results suggest that oral probiotic supplementation may help speed up healing of the skin after UV exposure.
Eur J Dermatol, 2008; 18(5): 504-511.
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