Opening Line of this Paper tells a Sad Tale

Ann's NOTE: Below please find the opening statement of a paper dealing wtih a new 'prodrug'. I was struck with the information it contained. Often we gather information from unlikely sources, in unlikely ways.

Anti-tumour activity and toxicity of the new prodrug 9-aminocamptothecin glucuronide (9ACG) in mice.

Prijovich ZM, Chen BM, Leu YL, Chern JW, Roffler SRInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan 115, and ICTM, Center for Chemistry, Belgrade, Yugoslavia.

Cancer chemotherapy is limited by the modest therapeutic index of most antineoplastic drugs.

Br J Cancer 2002 May 20;86(10):1634-8

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