ABSTRACT: Photodynamic therapy palliation of chest wall progression
from breast cancer in heavily radiated treatment fields
Purpose/Objective: Despite advances in the treatment of breast
cancer, a significant minority of patients will develop symptomatic
chest wall recurrence.
Radiation therapy salvage is possible,
but patients often re-recur and reach radiation dose limits.
examined the potential role of photodynamic therapy (PDT) in
this particular patient population.
Conclusions: PDT offers gratifying clinical and cosmetic response
in patients who have chest wall progression despite receiving
high cumulative radiation doses.
The drug/light combination
employed appears to offer excellent response rates that are
durable without inducing painful fibrotic tissue changes.
should be considered as a viable salvage modality for these
[11/08/2002; International Journal of Radiation Oncology, Biology, Physics]
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