Articles

June 2008

***Science: Lymphomas According to researchers of the Karolinska Institute in Stockholm, Sweden, high CB1 and CB2 receptors levels are found in most non-Hodgkin lymphomas. Cannabinoids induced cell death in these cancer cells. Researchers concluded, that "our results suggest that therapies using cannabinoid receptor ligands will have efficiency in reducing tumor burden in malignant lymphoma overexpressing CB1 and CB2." (Source: Gustafsson K, et al. Int J Cancer, 2008 Jun 10. [Electronic publication ahead of print])

February 2008

Spanish scientists investigated allergies to cannabis leaves. They found out that subjects with an allergy against tomato have a high risk to also have an allergy to cannabis leaves. (Source: de Larramendi CH, et al. Int Arch Allergy Immunol 2008;146(3):195-202)

April/May 2006 FDA Announces Decision - Medical Marijuana is NOT Approved.

Many disagree with their findings, particularly in light of the 1999 Institute of Medicine report citing potential benefits. All agree more research is needed. Advocates think FDA will stand in the way as DEA has done (Drug Enforcement Administration).

It Is Time for Marijuana to Be Reclassified as Something Other Than a Schedule I Drug

Posted 08/26/2005

George D. Lundberg, MD Source: MEDSCAPE

For many decades, marijuana has been the American poster child for how not to deal with a troubling psychoactive substance. By US law, a Schedule I substance is one with no recognized medical use and great potential harm to the user.

Marijuana has been classified as a Schedule I substance for many decades,[1] along with heroin and LSD. Judging from its easy availability, low cost, and widespread current use, such a restrictive classification has failed to retard its use. In fact, enforcement of unrealistic laws regarding marijuana has probably caused more harm than marijuana itself.

Although far from harmless by toxicologic or pathologic criteria, marijuana is much less dangerous than many other substances in less restrictive schedules, like morphine and cocaine, not to mention the unscheduled legal mass killers tobacco and alcohol. Of course, marijuana does have proven medical usefulness for some conditions.[2]

People obey laws they believe to be just; they do not obey the marijuana laws because they know they are unjust, even absurd. Kids quickly see through lies. Many kids may discount the proper scare tactics about really dangerous drugs, like heroin and PCP, because the dangers of marijuana have been so overstated.

Ninety percent of Americans believe that the federal government should not prosecute medical users of marijuana, despite the newest "federal foolishness" of the recent Supreme Court decision against it.[3] This commonsense position of the people should give pause to any overzealous prosecutors who might have real trouble finding a jury that would convict a seriously ill user of medical marijuana.

The court decision now provides the Congress and the Drug Enforcement Administration with a sterling opportunity to join with the population they are supposed to be serving and with the good science of the 10 states that have authorized the controlled use of medical marijuana and reclassify it at some level other than Schedule I.

That's my opinion. I'm Dr. George Lundberg, Editor of MedGenMed.

References

Department of Justice. Drug Enforcement Administration. Marijuana scheduling petition: denial of petition: remand (Pocket No. 86-22). Fed Regist. 1992;57:10489-10508.

Kassirer JP. Federal foolishness and marijuana. N Engl J Med. 1997;336:1184-1187. Available at: http://content.nejm.org/cgi/content/short/336/5/366 Accessed August 19, 2005.

US News - MSNBC.com. Should the federal government prosecute medical marijuana users? Available at: http://www.msnbc.msn.com/id/8118359 Accessed August 19, 2005.

George D. Lundberg, MD, Editor-in-Chief, Medscape General Medicine; Adjunct Professor of Health Policy, Harvard School of Public Health, Boston, Massachusetts

Sent 8/30/05 by Ann Fonfa (Medscape asked to publish this)

Dear Dr. Lundberg,

Once again a marvelous editorial, and much needed. We have beer commercials that make fools of young men at the same time as marijuana persecution continues.

Cancer patients whisper to each other of their desire to 'try' it to relieve unbearable nausea while studies show it may have many other medical uses.

Thank you for speaking up.

Ann Fonfa President The Annie Appleseed Project www.annieappleseedproject.org

Politics harming research on marijuana's anti-cancer properties?

by Indo-Asian News Service , New Kerala September 22nd, 2004

Health India] Washington, Sep 22 : Even as research findings confirm marijuana's anti-cancerous properties, a stoic disinterest on the part of the US government to fund further research raises questions about its priorities, UPI reports.

Results of clinical research at Madrid's Complutense University showing components in marijuana derived from the cannabis plant inhibits the growth of cancerous brain tumours have been published by the journal of American Association of Cancer Research.

The finding that cannabis restricts the blood supply to Gliobastoma multiforme tumours, an aggressive brain tumour that kills some 7,000 people in the US every year, has been released in the backdrop of scant media coverage of the topic in the US as its government has not acknowledged the research abroad.

That is despite the fact that the first experiment documenting pot's anti-tumour effects took place in 1974 at the Medical College of Virginia at the behest of the US government.

The results of that study, reported in August 1974, were that marijuana's psychoactive component "THC slowed the growth of lung cancers, breast cancers and a virus-induced leukaemia in laboratory mice and prolonged their lives by as much as 36 percent".

Despite the early success, US officials banished the study and refused to fund follow up research until conducting a similar -- though secret -- clinical trial in the mid-1990s.

That $2 million study, conducted by the US National Toxicology Programme, concluded that mice and rats administered high doses of THC over long periods had greater protection against malignant tumours than untreated controls.

However, government researchers shelved the results, which only became public after the findings were leaked in 1997 to a medical journal, which in turn forwarded the story to the national media.

Since the completion of that trial, the US government has yet to fund a single additional study examining the drug's potential anti-cancer properties leaving room for conjecture whether federal bureaucrats were putting politics over health and safety of patients.

Scientists overseas picked up where US researchers abruptly left off.

In 1998, a research team at Complutense's Department of Biochemistry and Molecular Biology discovered that THC could selectively induce programme cell death in brain tumours without affecting healthy cells.

In 2000, they reported in the journal Nature Medicine that injections of synthetic THC eradicated malignant gliomas (brain tumours) in one-third of treated rats and prolonged life in another third by six weeks.

Last year, researchers at the University of Milan in Naples reported that non-psychoactive compounds in marijuana inhibited the growth of glioma cells in a dose-dependent manner and selectively targeted and killed malignant cells through a process known as apoptosis.

Researchers reported earlier this month that marijuana's constituents inhibited the spread of brain cancer in human tumour biopsies from patients who had failed standard cancer therapies.

Indo-Asian News Service, 9/04

Our source: www.safeaccessnow.org


HR2592 State's Right to Med MJ Act

Support our rights

Rescheduling Petition Filed with DEA
Fed Appeals Ct Okays Med Use Under Certain Circumstances
Medical Marijuana Victories March, 2004
Vermont to Allow Medical Marijuana
Montana and Legalization of Med Marijuana
Hawaii Enacts Medical Marijuana Law
More on California's Law
Nevada Medi-Pot Program Begins
New Mexico Legislature Approves Med Marijuana
Rhode Island Medical Marijuana Law Now Permanent
Marijuana  & Pain Relief

Study 8/00 show may work when morphine fails with spine/nerve injuries (possibly neuropathy from taxanes?)

Management of Pain: Systemic Review
MS & Cannabis-Pain Relief
Analgesic Effect of Synthetic Cannabinoid CT-3
Singer Melissa Etheridge Says Med MJ Helped Chemo
Cannabinoids: Pain Relief, REVIEW
Synthetic Cannabinoid Nabilone Improves Pain & Symptom Mgmnt in ca pts
Medical MJ reduces Post-op Pain
Med MJ and Peripheral Neuropathy
Anti-tumoral Action of Cannabinoids

Nat Med 2000 Mar;6(3):313-9

Skin Tumors Inhibited by Cannabinoid Receptors
Novel Approach to Anti-Cancer Therapy
Antitumor Effects:Cannabidiol & Brain Tumors
Marijuana & Metastatic Spread
THC Inhibits Tumor Cell Growth BETTER Than Synthetic Alt
Smoking of Cannabis DOES NOT Increase Risk:Oral Ca
Cannabinoids & Cancer: Review Article 2005
Cannabidiol Inhibits Breast Ca Cell Growth
-9 Tetrahydrocannabinol inhibits growth & metastasis of lung cancer
endocannabinoid system in cancer potential therapeutic target?",
Med MJ NO Interference w/Irinotecan or Docetaxel

The Oncologist, 3/07

NaturesPerfectOil

LINK to product using the medicinal properties of organic hemp seed oil

Hemp & Hemp Oil Phoenix Tears

LINK to Rick Simpson's site Canada

Not much Appetite Boost Derivative at these Levels

CNN story, May 15, 2001

Smoking Marijuana May Increase Risk of Heart Attack (a little)
Patient Perspective
Cannabinoid For Appetite Control
Respiratory Effects of MJ & Tobacco
THC Shown to Enhance Kaposi's Sarcoma (BAD effect)
Anti-Vomiting Component Isolated

Study in J Neuropsychopharmacology, February 2001

Cannabinoids Control:Chemo-induced Nausea/Vomiting
Cannabinoids Inhbit Vomiting at 5-HT3A Receptors
How To Use Nabilone: Approved Methods & Information
Am Medical Assoc Supports Research (other groups too)

June 2001

Therapeutic Benefits Shown
Anti-Tumoral Action of Cannabinoids (rats)
Am Nursing Association Backs Patient Access to Med MJ
AARP Survey: 3/4 Seniors Favor Legal Acess Med MJ
THC May Protect Blood Vessels From Clogging: Med MJ

Nature, 4/05

Study of Med Mariju in CA-AIDS Patients

Cable News Network (AP) 4/01

Evaluation of herbal cannabis by medical users in
A Way to Make Pot Legal for Patients

Boston Globe, May 18, 2001

68% of Americans Support Medicinal Pot
Medical Pot Legal in Canada

Source NORML News, Vol 4 28.0

Canada Lets Terminally Ill Grow, Smoke Marijuana
MJ Extracts for Pain Study in Canada
Health Canada To Fund Clinical Trial
Health Canada Regs Authorize Sale of Cannabis/Pharmacies
Canada Set to Approve Sativex
Enzyme as Medical Marijuana Alternative

Reuters Health, 7/24/01

CAZ Speaks: Ca Patient &Homeopath

Advice/Information

DEA Okays First Med Trials in 20 years

Three studies approved, 12/01

The Marijuana Mission

LINK to a site for information and more

Lombardy (Italy) Approves MJ-based Medicines

Reuters Health, 5/01/02

New South Wales Okays Clinical Use of MJ
Pharmaceuticals Start Trials

Phase III begins, 1/02

Testing Cannabis Spray
Department of Health UK, Report
Developing a Metered Dose Inhaler
Sativex Approved in Canada
Therapuetic Benefits

J Cannabis Therapeutics, 2/02 Few Adverse Effects in Long-term smokers

Marijuana Use Appears Unrelated to Lung Cancer
Pharmacological & therapeutic secrets of plant & brain (Endo)cannabinoids
Nabilone Effective for night sweats in Cancer
Nixon Tapes Show Why US Outlawed Pot

Kevin Zeese, AlterNet 3/02

Clinical Trial of THC for Cancer (Spain)

Reuters, 3/25/02

NSAIDS & THC
Dutch Parliment Favors Legalizing Med Marij

AP, 4//08/02

Cognitive Functioning-Long-Term Users

JAMA, 5/02

Letters on Study of Long-term Cognitive Deficits
Do Not Smoke and Drive
Marijuana Promotes Neurogenesis - Develops NEW neurons
Initiative in Arizona:Medical Marijuana

8/02 On the Ballot

Gov't CANNOT Revoke Doc's License

9th US Circuit Court protects doctors

Cannabinoids

Excerpts from Medscape 3/03

FDA Approves Trial:Inhaled MJ Vs Vaporized

NORML News, 12/03

Vaporizers Reduces Toxins Assoc w/Smoke
NIDA Rejects Cannabis Vaporizer Study
Assessing the effects of cannabinoids w/ a less jaundiced eye

J Hepatology, 1/07

Join Medical Marijuana Patients' Union

www.safeaccessnow.org

History of Cannabis & Its Preparations

Chemistry & Biodiversity August, 2007 online

Natural Medicine - Dr. William S. Eidelman

LINK to site with info on medical use of cannabis "non-drug therapies for pain, anxiety, depression" and more


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