Fine Needle Aspiration/Stereotactic Core Biopsy

ABSTRACT: Fine Needle Aspiration May Shed Breast Cells into Peripheral Blood as Determined by RT-PCR

Objective: A diagnostic test applying reverse-transcriptase chain reaction (RT-PCR) assay targeted against cytokeratin 19 (CK19), cytokeratin 20 (CK20) and the [beta]-subunit of human chorionic gonadotropin ([beta]-hCG) mRNAs was used to evaluate the impact of fine needle aspiration (FNA) on breast cell shedding into peripheral blood.

Conclusion: FNA to breast tumor may cause hematogenous dissemination of breast cells.

Ann's NOTE: What this means is that like a surgical biopsy, it is possible to spread malignant cells through the blood stream by the fine needle aspiration. (NOT GOOD NEWS).


Needle Biopsy & Sentinel Node Metasases:Breast

Arch Surg, 6/04

Stereotactic Core Needle Biopsy

The Breast Journal June 2001

Clip Migration After Stereotactic Biopsy
Breast Mass Removal Via Lump Extractor

Eur J of Surg Onc, 8/01

Four Needle Biopsy Optimal

Br J Surg, 2/02

Prognostic Significance of Tumor Cell Proliferation (FNA)

Breast Cancer Research & Treatment, 1/02

Gene Expression Correlates w/Response to Chemo

Breast Cancer Research, 4/02


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