Fat Increased Risk/Fruits/Vegs Decreased Vaginosis

Dietary Intake May Affect the Risk of Bacterial Vaginosis in Women

"Dietary Intake of Selected Nutrients Affects Bacterial Vaginosis in Women,

" Neggers YH, Nansel TR, et al,

J Nutr, 2007; 137(9): 2128-2133. (Address: Yasmin H. Neggers, Department of Human Nutrition, University of Alabama, Tuscaloosa, AL 35487, USA. E-mail: yneggers@ches.ua.edu ).

Summary: In a study involving 1,521 subjects (86% African-American; participants in a larger study on vaginal flora), dietary fat intake was associated with an increased risk of bacterial vaginosis (BV), while intakes of folate, vitamin E, and calcium, were associated with a decreased risk of severe BV.

Of the subjects, 42% had BV. 14.9% of subjects had severe BV (Nugent score of 7 or greater). After adjusting for other energy nutrients and behavioral and demographic covariates, BV was found to be associated with increased dietary fat (1.5), severe BV was found to be associated with total fat (2.3), saturated fat (2.1), and monounsaturated fat (2.2).

Overall energy intake was marginally associated with BV (1.4; p=0.05).

Significant inverse associations were found between severe BV and intakes of various nutrients, including folate (0.4), vitamin E (0.4), and calcium (0.4). The results of this study suggest that consumption of fat may be associated with an increased risk of BV an d severe BV, whereas intakes of folate, vitamin E, and calcium may reduce the risk of severe BV.

August 2007

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