Familial Breast Cancer in Egypt

Profile of familial breast cancer in Alexandria, Egypt.

Bedwani R, Abdel-Fattah M, El-Shazly M, Bassili A, Zaki A, Seif HA, Weber W

Medical Statistics Department, Medical Research Institute, Alexandria University, El-Hadara, Egypt. cmtalex@alexnet.com.eg [Medline record in process]

Nearly two thirds of the cancers which will appear in the next 25 years will occur due to unawareness of the public. In a population genetic study in Alexandria, Egypt, we found that the parents of 20% of the population are first degree cousins. Out of 9,587 female cancer cases registered in the last 10 years by the Alexandria Cancer Registry, 3250 (33%) were breast cancer.

Twelve percent of breast cancer patients had a positive first-degree relative family history of cancer. Familial breast cancer (FBC) occurred at a younger age, ranging from 23-74 years, with a median equal to 46.5 years compared to 35-76 years, with a median of 54.5 years, in non-familial cases.

The aim of this work was to show how familial cancer registries can produce useful data, helping to develop a data base of familial cancer, for the primary care program to control the morbidity of breast cancer in females by identification of those with a positive family history of cancer who are at a high risk of developing breast cancer.

Anticancer Res 2001 Jul-Aug;21(4B):3011-4

PMID: 11712803, UI: 21569221

Egyptian Women & Treatment Decisions

The Breast Journal, 4/03

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