TSWAHL: Is the use of progesterone cream safe after breast cancer and is it effective
if the tumor was PR-neg?
Dr. John R. Lee: The test for progesterone receptor presence or absence is not a very
accurate test. Progesterone receptors are stimulated to be made by estrogen itself.
It is highly unlikely that any tumor driven by estrogen would have no cells that
lack progesterone receptors. If there in truth were no progesterone receptors then
it could do no harm because the cell could be unaware that any progesterone is
present. Chances are the receptors are there, and therefore the cell will respond
to the message of progesterone which is a prevention against breast cancer.
If a phone line came by your house, but you didn't have a phone, you would be
unaware of it -- that's how it is with progesterone. The message of progesterone
to breast cells is to stop them from becoming breast cancer cells.
there is no reason ever to not give progesterone to try to help someone prevent
or stop breast cancer.
In 3,000 breast cancer biopsies Dr. Zava found only one in which there were truly no
progesterone receptors. It's a rare congenital defect.
Dr. Lee has written a paper: Annals of Clinical and
Laboratory Science, 1998, Vol. 28, page 360, June. "Progesterone inhibits growth
and induces apoptosis in breast cancer cells: Inverse effects on Bcl2 and P53."
Ann's NOTE: We were unable to access this journal online. If anyone can get this article, please email it to us and we will post it.
And according to his associate, Brent Formby, he has two more papers about to be published.
From a powersurge.com chat in March, 2002
Article references found here
LINK to his site
LINK to site for
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