Cannabinoids Offer Novel Approach For Treatment Of Prostate Cancer
The administration of synthetic cannabinoids inhibits
malignant cell growth in human prostate cells in vitro in a dose-dependent
and time-dependent manner, according to clinical trial data published in
the March issue of the journal Cancer Research.
Researchers at University of Wisconsin's Department of Dermatology
reported that the administration of the cannabis receptor agonist
WIN-55,212-2 inhibited cell growth in certain human prostate cells, and
also induced apoptosis (programmed cell death). Administration of a
cannabis receptor antagonist prevented these effects.
"Our results suggest that ... cannabinoid receptor agonists (a drug or
chemical that combines with a receptor to produce a physiological reaction
typical of a naturally occurring substance) could be developed as novel
therapeutic agents for the treatment of prostate cancer," authors
Previous trials have found cannabinoids to induce tumor regression in
rodents and in human cells, including the inhibition of lung carcinoma,
glioma (brain tumors), lymphoma/leukemia, skin carcinoma, and breast
For more information, please contact Paul Armentano, NORML Senior
Policy Analyst, at (202) 483-5500. Full text of the study, "Cannabinoid
receptor as a novel target for the treatment of prostate cancer," appears
in the March 1 issue of Cancer Research.
Ann's NOTE: We have a large section on medical marijuana in the Studies area (see left of page). Located in the Non Toxic section therein.
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