ABSTRACT: Breast-conserving therapy for Paget Disease of the nipple:
A prospective European organization for research and treatment
of cancer study of 61 patients
BACKGROUND: The purpose of the current study was to assess the
outcome of breast-conserving therapy by means of a cone excision
and radiotherapy in patients with Paget disease of the nipple
without associated invasive breast carcinoma.
CONCLUSIONS: Breast-conserving therapy is a feasible alternative
for patients with Paget disease and a limited extent of
underlying DCIS. To achieve good local control, treatment
should be comprised of a complete excision of the nipple-areolar
complex including the underlying disease, followed by irradiation
to the whole breast.
J Cancer, 5/03
Current Treatment Options in Oncology, 3/04
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