ABSTRACT: Breast cancer in relation to induced abortions in a cohort of Chinese women
The possible influence of induced abortion on breast cancer
risk was assessed in a cohort of 267,040 women enrolled in a
randomised trial of breast self-examination in Shanghai, China.
Based on answers to a baseline questionnaire, subsequent breast
cancer risk was not significantly associated with ever having an
After adjustment for potential confounders,
the relative risk estimate was 1.06 (95% C.I.: 0.91, 1.25), and
there was no trend in risk with number of abortions.
data from more detailed interviews of 652 cases and 694 controls
from the cohort yielded similar results. There was also no overall
increase in risk in women with induced abortion after first birth.
Few women had undergone an abortion after 13 weeks gestation or
before their first child. Although increases in risk were observed
in such women, they were not statistically significant and could
have been due to recall bias.
Abortions as they have been performed
in China are not an important cause of breast cancer.
[10/23/2002; British Journal of Cancer]
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