Anti-malignin antibody in serum and other tumor marker determinations in breast cancer.
Cancer Research Institute of West Tennessee, Henderson, TN 38340, USA. email@example.com
In this study, 154 healthy volunteers and 76 patients were tested using the anti-malignin antibody in serum (AMAS) test. Of the 154 volunteers, three were AMAS positive. After further examination, two were positive for cancer and one had a history of ulcerative colitis.
Tumor biopsies of 43 suspicious mammography patients revealed that 32 were cancerous and 11 were benign by pathology. For the cancer patients, 31/32 were positive for the AMAS test, while 4/11 of the pathological benign cases were AMAS positive.
In comparison to cancer antigen tests, AMAS was more sensitive (97%) in detecting breast cancer than CEA (0%), CA 15-3 (10%), CA 19-5 (5%) or CA 125 (16%) in the same patients.
Cancer Lett. 2000 Jan 1;148(1):39-48.
Int J Biol Markers, 10-12/97
Cancer Detect Prev, 1994
Cancer Epid Biomarkers
& Prevention, 10/05
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